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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e90c9cd75543a6e956f28d02ce23a09dd718f3e6ad0127c1caea90b5b0cde09' 
  AND token = '6HMFWNLUOXCHFlJzAptK2tPizPFhU194O+2nAh/jnyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}