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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2da0d069dc9ccca938690ff5232279a24f04b6799f9d90b7b6382a0f3e2b314' 
  AND token = 'UHwOceAKF0/BFM+WMnUMjtdqnhd2BAP9kt7S5f+56Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}