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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64d1d008f69d9b34a147c3f676043f6cff926697edc965ed11f7588a9dfc03af' 
  AND token = '6S7/Z0KUVVEqVeOEEKgxwz3GAVr+r5MPtxkNDZLU/uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}