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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc174795e1f41928bbf9242abc0212f6f58b9b1741ed3527bc31f1a844375a64' 
  AND token = '4SIJoE2WKWM3efTInvU3fFR8FN3m1WVbNgwlrqBdFvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}