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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd61a3796bfae4c1c2a121df9b9fa3f68898a7a41c40f0d9151d1c53883cb78' 
  AND token = 'Le6ca2UrQkY/tT4vWXWu7UNT4p4Fxz3h62iBN31bE7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}