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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3996a41072d1ca6f6db18cb6ceb7591a106e66692ac0f93e2e10294cc9faafbc' 
  AND token = 'eTATNEPSQxfzphBbZ+ekzY2eqfC2Sv0dwRfN8aL83bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}