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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c1f6f4a6a237e61422baeed6f6f78817a1ed5f95c4db6567886a334ba14f6d2' 
  AND token = '6vYhJXOgcYG0q6p6tzY6TDDqUbpBOrwJYOrQNRiqNm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}