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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '483922257c2e3b9c51f8782e63a2f5164dcfcb00c5fb56984e354d1d549561b8' 
  AND token = 'ZiUa0kTMeUsERLSb0xJb5W2N9kSqoLNOvNL1Qr2JSa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}