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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed588c317dd914e783af391ecf39031705457430f7c0b320e749879a6ed2eef' 
  AND token = 'tUEC9bzXrbYFzFyzLsPz5X9q+XK8bVZVQBnJ1SUS7f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}