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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e84d6250e5e7144649cb4053c53e579b8650f7d1e7e30fedb2cc624115081755' 
  AND token = '/0Z7upedApsopyria5Uf73QgIuE1Dk08pZU2+tW14ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}