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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52642a708066f206f57a5162d77a4be97c40f8c62e211e19f8d37a09893b9a7a' 
  AND token = 'aXLJSyeBB7A4zFBFAQcha6RLMaAmy8665nEW0ZO9IrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}