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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd546310ce3d93521d35cc3ee73ca17c297e4b8d9eed0b6017c1bcc738d45d8c' 
  AND token = 'MtaMRCMzGKS4R6wUKK9N+P+BbxuoezNM80asP5GnQvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}