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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ac4fca4c45d7b1b5312811796c4eb7e92affa189f571d6d7a80dbed1c993794' 
  AND token = 'G8JFa9tviaKX6sMCoAbmPEwj+P7wPHOMCC0DQ8CSgYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}