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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ee48f6e928338a1d902917716c75a58cdb9fd5b3677565dd0351470861dd31' 
  AND token = '9624wWrRMqdlxKmLtwvc30C1ORhMp3Se0ELjMW9EWwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}