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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '650e7d68384ad7e5aee82ab90d63d78dbfa5b24b096d59a089e45ac5c90d41f9' 
  AND token = 'DG0UsBKr+gx0PUvQMhcc7V4VCTXsCqGrRVc2GqcUGp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}