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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5202493c7c19409a8a07161f04aba0b1195b4ee6113a8bbe840319184ce1ecb9' 
  AND token = 'yH8z+Ydx2eNYlmh2gaswMedZWKbH/YEMdHfB7ZzuKe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}