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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446420867aed7fca590c45f0cbc05790c492b85f6f349232cc92d8594635c69f' 
  AND token = 'ulQLuzKbo7Zp8iRfO9ckC//JMe2N/hILTxfhe7S7WPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}