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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '777a044d86e978f6fdeffa5772ada43f88e7ad60c840d3a298cf8ffc21960cbb' 
  AND token = 'XCfYXwNvVSkIDYXo9EWdBgaNNuPZq8ia9IQ7/M/I2oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}