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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43e77da4ea214e81cf05240940464fbb8cfb8e3977747fe0ccb527a2a2227c3' 
  AND token = 'uGI+1Ucxb7XvNnZdSFLuqj2f1j0HVZn2EpDck7s5UHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}