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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b444b191451e78c7ad4cd8e6a31a2bcaa664d9590a6d5252d1e7912e8f6f1496' 
  AND token = 'TbipesYl6bSaIP0xyUZb8OH+p2uxVYBSftCvdDCwEaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}