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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78e6935bebb21785014bf43389a456e98e6bd2a478a8a3458535c2d162f5f61' 
  AND token = 'p7XiquO2mdMetNdyetgTem1m8gkfg5KlrKVcUly+Jqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}