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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ce805c4296e2cc0da87c175b1827b8fa2df50d58375e33a9a46a8974fcfb701' 
  AND token = 'WF/3YSzgGyWb2jsDORuPzvKLUv7xkDAH5fHy8NOIB4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}