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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a789dc481de774f755be4cb2ea3802f408c250f0c257dda931ab238b0fd4d7' 
  AND token = 'JiOqHy5651o01RW/MSPOUyaKzCThA2nGgPbtff9flrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}