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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '145453329eb2f3cfea6d82ecc5fc0adb98f1e85116daac43e20f67ccf01d8abd' 
  AND token = 'Q++8EcRtAsT+vxLjGL6Ql4Jk/5fcJ+jdRAL8Z6vLMsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}