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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c3b1fc271d150c9e171bdb3d048d8e3548dae48b2c6c35350c61e34c0f4a901' 
  AND token = 'Vg6NPR2XpUc/7AlwgfDzfQanGLhVMxuAFI9nhke2Yyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}