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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65850eb1e29e4b9bb803d2bd9b1a9b50ff0b479007b664d989a894e7079de3ee' 
  AND token = 'FPC8EBeTaqoMT3z52ku2hTJxtG0gqTwGxEJHBdErYjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}