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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e8665c31427301e914f7142fff6e058ef061073bfacf0daa7b6a970246afa7a' 
  AND token = 'zdGHAFWPUAabzDJKL5OAI6APTYpxB3WQCtBbB5HHZ7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}