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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '332896cf492bf40059976cb909d6f5ea4d84ec58143a7738f5707c240afc8408' 
  AND token = 'u+O6+XMOPbJqO2JsBRYzPrkNODSHuRUtJrTEZdNk0Bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}