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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a4812df9b6e262820684d40d27a8b8992936ab0ed37e68097f3992ee176d521' 
  AND token = 'oXPvtCpNtJ+o6+A4cfeuMT1XjJFNHG/0PWiTWUDP/bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}