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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '560b25c66922850b34bc902c2f11eb946551dec7d7b980ade0cfbefe1390a0a1' 
  AND token = 'hp7+kBH3DCNZOKd9nr/bDrHghUIttAPsu5NRUVrTZ+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}