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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07eb70073e37c0badbdd6a8e282ebccb9527fc9c7e4f834c920bd9be8ea1944d' 
  AND token = 'p1MHmXjwCYebv3XVjTe8ZWjz65YZTVJg2VCN6qds7Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}