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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c88f49d22ce0b15ce364e725efa18b0cbdb04624f44bcb86d53a5a7bd500264' 
  AND token = 'mZuriUVWK0kmPOmqBNKzQEitF0ESVS9lRWk1xDtOu4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}