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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f49b17874e9cbf613a59efff745bffc5117ed967628e73201f26a9343bd47d2d' 
  AND token = 'n40XZfbqwxw1Km3uw5wwKic9ChMar5nqHwfsvj0AyIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}