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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '860ed548454b9e25c030df367f55542244cad8fd2f956a2ef61a7145d3b32688' 
  AND token = 'BCh6WvYt85pwJ5Y+8LOj0NhAZVaAbwDbbxpWuxeLhUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}