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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77cd71d02ff3025b4a89764659fca31db238d8f21f1d19c9d2d04e0b14453bc3' 
  AND token = '6EHMVTVCtiERaYTYEGM493SHgjku+zY3cw62a0Ng8Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}