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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fed17cc2ff7ba36443be9bd9574ec94bc1374426ea906f738e2c105f61aa746' 
  AND token = '5C/rIn6cHM6WS8KITsq4v19b53AH+VqMJRKGtQW3GaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}