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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b496b0fbc8e96fc9abaa17a5aa21f4550da2721ab80a39600bc954f3d0310eca' 
  AND token = 'IuIniDb2b4uFm345FPb5UN7di9HE3NVFbaPM3VWLlaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}