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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f16ebe0cef22466b21845a1c292c6e5ffc65a3d2c44eb7db2a5b88e3ed195d0' 
  AND token = 'nsWgTocVCgdic484dB9+eym68Pvaj6MNjkT0OsPlzmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}