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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001042ba8690ca0fcadecdb902c8eb6f85dc8211e7d270bf6b08061f6ec218b2' 
  AND token = 'wF1045lukWEmw+ns3XA945gjerkDC9hpVERjdM9NUOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}