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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00249d41b20bc793ebbf17138a32e60ed7aa0681a00112f5d5ecdf5c7e886765' 
  AND token = 'Yf2ycnLL2rPX0APDNgVdbxSaV+L8a46PXg3JpHL8Fp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}