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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5549d68d3b65542b9b529b21f19b708611cdae2a07837acd0d43c9e11ca4afe9' 
  AND token = '9i5RuBL7rwW/XWxoDv8uf1ktZeCIWxz4i54pUVGKeqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}