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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3c133e53e89ec5c02777d5ea0c190214dd0b296fc4fcde22521338e8d6b8cf0' 
  AND token = 'GDdqcR0ti9onw51/fTa1o+fM3zBSHsLQMk/+SH8Xbao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}