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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1df12884d53152bbb58d666d45b9e6c80cd1f4679b7fd01f8ea2656e8fea0096' 
  AND token = 'KyTMQTSOiIazNDVEt5aiWjwX9uY8JTTJJAxKGeqI7Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}