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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22738c0508571c255ca24e3253154b1c83210677abd1abde93dc1b61b500b40a' 
  AND token = 'YKx1w2eL6ORlsY3mMauKMQzaZhLmDjB9/So+r6ilDJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}