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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a46bf936ed3186bfaec6b8f8f7f6cbbc7879bd36647f91f75c30b52bb3466e4' 
  AND token = 'tzRtjWD03tI4jRLdewHEGzhvTknEoL2AtQG4KD7LfUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}