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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c34e4ba5933966c26184dfec19be1abb4b24d5d49a934a03b5363c8e872fffdc' 
  AND token = 'JQU6mXgx038iAinBfY5aIrWy/xPe1G7mmaVdkOTg5vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}