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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a193be0fe5f78eb47e76919da5f2c5dc5f0cdec222738a60dddd23514fa6681b' 
  AND token = '5SWRFpjce9T+pEqTguhCTT6Uuq4q/4jjWNdxdXgJRR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}