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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e79fbfb522869e1d6cb65c077eda5cdbdad1183f399e13e3f03674f07473cd2' 
  AND token = 'h5nXoCFOnkRMPpk9dc0FfoN5CHbFRRJRjAfqz0DWra0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}