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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821ae8260407234ed1adae697cb291a369efed0225b93f24a39f5a5929018e66' 
  AND token = 'PPtFupB3rNYNSn+Zc0FpRtVin57IzOj5EuV4F9ruy8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}