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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3af7430432d2f8d47f59a1b3231d9255e174de4d7da1dd54ff11977ccf8e865' 
  AND token = 'DCwjbwyBSbn6/2bLiOp9R3XSUrCXCl5E7pQAgOK4p1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}